高新的個(gè)人首頁(yè)

高新醫(yī)生簡(jiǎn)介

  職  稱(chēng):教授/主任醫(yī)師

  導(dǎo)師資格:博士研究生導(dǎo)師

  最高學(xué)歷:博士研究生、美國(guó)耶魯大學(xué)醫(yī)學(xué)院博士后

  畢業(yè)時(shí)間:1997年2月

  主研方向:一直致力于前列腺癌早期診斷,前列腺癌微創(chuàng)手術(shù)為主導(dǎo)的綜合治療以及前列腺癌早期診斷技術(shù)和轉(zhuǎn)移的分子機(jī)制等方面研究。

  社會(huì)兼職:衛(wèi)生部?jī)?nèi)鏡與微創(chuàng)專(zhuān)業(yè)技術(shù)全國(guó)考評(píng)委員會(huì)全國(guó)泌尿科內(nèi)鏡與微創(chuàng)專(zhuān)業(yè)委員會(huì)主席、中華醫(yī)學(xué)會(huì)泌尿外科分會(huì)全國(guó)委員、廣東省泌尿外科學(xué)會(huì)副主任委員;《中華腔鏡泌尿外科雜志》主編。

  醫(yī)療專(zhuān)長(zhǎng):能夠熟練診治泌尿系統(tǒng)疑難疾病, 尤其擅長(zhǎng)前列腺疾病的微創(chuàng)治療;2000年在國(guó)內(nèi)完成首例腹腔鏡前列腺癌根治術(shù),目前在國(guó)內(nèi)報(bào)道病例數(shù)最多;積極創(chuàng)新手術(shù)方式,如開(kāi)展保留性神經(jīng)和控尿神經(jīng)的腹腔鏡前列腺癌根治術(shù);開(kāi)展神經(jīng)電生理監(jiān)測(cè)數(shù)字化的腹腔鏡下前列腺癌根治術(shù),開(kāi)展單孔腹腔鏡前列腺癌根治術(shù);開(kāi)展經(jīng)膀胱單孔腹腔鏡下前列腺癌根治術(shù)等。

  獲獎(jiǎng)情況:2011年廣東省科學(xué)技術(shù)獎(jiǎng)一等獎(jiǎng):前列腺癌的分子診斷與微創(chuàng)治療 (排名第一)

  2006年廣東省科學(xué)技術(shù)獎(jiǎng)三等獎(jiǎng),2008年教育部科技成果二等獎(jiǎng):腹腔鏡泌尿外科成形與切除手術(shù)的臨床研究及應(yīng)用推廣(排名第一)

  論  著:1. Gao X*, Pang J*, Li LY*, et al. Expression profiling identifies new function of collapsing response mediator protein 4 as a metastasis-suppressor in prostate cancer. Oncogene. 2010 Aug 12;29(32):4555-66. (SCI, IF 7.414)

  2. Gao X*, Li LY*, Zhou FJ*, et al. ERG rearrangement for predicting subsequent cancer diagnosis in high-grade prostatic intraepithelial neoplasia and lymph node metastasis. Clin Cancer Res. OnlineFirst 2012;doi:10.1158/1078-0432.CCR-11-2449. (SCI, IF 7.338)

  3. Pang, J., Liu, W. P., Liu, X. P.,…Gao, X. Profiling protein markers associated with lymph node metastasis in prostate cancer by DIGE-based proteomics analysis. J Proteome Res, 9: 216-226, 2010. (SCI, IF 5.460) (通訊作者)

  4. Sun QP*, Li LY*, Chen Z,....Gao X. Detection of TMPRSS2-ETS fusions by a multiprobe fluorescence in situ hybridization assay for the early diagnosis of prostate cancer: a pilot study. J Mol Diagn. 2010 Sep;12(5):718-24. (SCI, IF:4.219) (通訊作者)

  5. Li LY, Lin Z, Yang M, Gao X,et al. Comparison of Penile Size and Erectile Function after High-intensity Focused Ultrasound and Targeted Cryoablation for Localized Prostate Cancer: A Prospective Pilot Study. J Sex Med. 2010 Sep;7(9):3135-42. (SCI, IF 5.393) (通訊作者)

  6.Ling, Y., Wei, K., Luo, Y., Gao, X*., and Zhong, S. Dual docetaxel/superparamagnetic iron oxide loaded nanoparticles for both targeting magnetic resonance imaging and cancer therapy. Biomaterials, 2011;32: 7139-7150. (SCI, IF IF:7.882) (通訊作者)

  7. Luo, Y., Ling, Y., Guo, W., … Gao, X*. Docetaxel loaded oleic acid-coated hydroxyapatite nanoparticles enhance the docetaxel-induced apoptosis through activation of caspase-2 in androgen independent prostate cancer cells. J Control Release, 147: 278-288, 2010. (SCI, IF IF:7.164) (通訊作者)

  8. Li LY, Yang M, Gao X, et al. Prospective comparison of five mediators of the systemic response after high-intensity focused ultrasound and targeted cryoablation for localized prostate cancer. BJU Int. 2009 Oct;104(8):1063-7. (SCI) (通訊作者)

  9. Li LY, Gao X, Yang M, et al.. Does a smaller tract in percutaneous nephrolithotomy contribute to less invasiveness? A prospective comparative study. Urology. 2010 Jan;75(1):56-61. (SCI) (通訊作者)

  10.Gao, X., Pu, X. Y., Si-Tu, J., et al. Single-centre study comparing standard apical dissection with a modified technique to facilitate vesico-urethral anastomosis during laparoscopic radical prostatectomy. Asian J Androl, 2011;13: 494-498. (SCI)

  11.Gao, X., Wang, K. B., Pu, X. Y., et al. Modified apical dissection of the prostate improves early continence in laparoscopic radical prostatectomy: technique and initial results. J Cancer Res Clin Oncol, 2010 ;136: 511-516. (SCI)

  12.Di JM, Pang, J., Sun, Q. P., Zhang, Y...Gao, X. Toll-like receptor 9 agonists up-regulates the expression of cyclooxygenase-2 via activation of NF-kappaB in prostate cancer cells. Mol Biol Rep, 2010;37: 1849-1855.(SCI) (通訊作者)

  13.Gao, X., Zhou, J. H., Li, L. Y.,et al.. Laparoscopic radical prostatectomy: oncological and functional results of 126 patients with a minimum 3-year follow-up at a single Chinese institute. Asian J Androl, 2009;11: 548-556. (SCI)

  14.Di JM, Zhou, J., Zhou, X. L., Gao, X. et al. Cyclooxygenase-2 expression is associated with vascular endothelial growth factor-C and lymph node metastases in human prostate cancer. Arch Med Res, 2009;40: 268-275. (SCI) (通訊作者)

  15. Wen, X., Li, X., Liao, B., …Gao, X. Knockdown of p21-activated kinase 6 inhibits prostate cancer growth and enhances chemosensitivity to docetaxel. Urology, 2009;73: 1407-1411. (SCI) (通訊作者)

  16.Wang, K., Gao, X., Pang, J., et al. Dendritic cells transduced with a PSMA-encoding adenovirus and cocultured with autologous cytokine-induced lymphocytes induce a specific and strong immune response against prostate cancer cells. Urol Oncol, 2009;.27: 26-32. (SCI) (通訊作者)

  17.Pang, J., Gao, X., Liu, X., et al. Enhanced antitumor effects by the coculture of allotumor RNA-pulsed dendritic cells with autologous cytokine-induced killer cells on hormone-refractory prostate cancer. Cancer Invest, 25: 527-534, 2007. (SCI) (通訊作者)

  18.Liu, X., Gao, X., Pang, J., et al. Proteomic analysis of rat penile tissue in a model of erectile dysfunction after radical prostatectomy. BJU Int, 2007;99: 1500-1505, (SCI) (通訊作者)

  19.WEN, X.Q.,HUANG, W.T.,SITU,J.,… GAO,X. Single-port laparoscopic radical prostatectomy: initial experience and technical points to reduce its difficulties.Chin Med J (Engl). 2011;124(23):4092-4095. (SCI) (通訊作者)

  專(zhuān)  著:主編專(zhuān)著兩部(《微創(chuàng)泌尿外科手術(shù)與圖譜》,廣東科技出版社, 2006年出版;《泌尿外科手術(shù)學(xué)》第三版,人民衛(wèi)生出版社,2008年出版)