曹旭晨,男,1986年畢業(yè)于天津醫(yī)科大學(xué)臨床醫(yī)學(xué)專業(yè),獲醫(yī)學(xué)學(xué)士學(xué)位;
2004年赴美國Vanderbilt University大學(xué)進(jìn)修分子腫瘤學(xué);
2005-2007天津醫(yī)科大學(xué)腫瘤學(xué)碩士畢業(yè),獲碩士學(xué)位;
2010-2013天津醫(yī)科大學(xué)腫瘤學(xué)博士在學(xué)
中國抗癌協(xié)會會員
中華醫(yī)學(xué)會會員
承擔(dān)課題
(1) "RUNX2基因在乳腺癌轉(zhuǎn)移及EMT中表達(dá)的意義及調(diào)控機制研究"天津市應(yīng)用基礎(chǔ)及前沿技術(shù)研究計劃(11JCZDJC28000),第一承擔(dān)人,20.0萬,6/2011至6/2014,進(jìn)展順利
(2) "藥物代謝酶基因多態(tài)性指導(dǎo)乳腺癌新輔助化療的研究"天津市科委面上項目(07JCYBJC09100),2006-2009,第一承擔(dān)人(2010年結(jié)題)
(3) "巨噬細(xì)胞系統(tǒng)在大鼠DIEP乳房再造模型中意義的研究,"天津醫(yī)科大學(xué)科研基金2006-2009,第一承擔(dān)人(2010年結(jié)題)
(4) "巨噬細(xì)胞系統(tǒng)在大鼠DIEP乳房再造模型中意義的研究,"天津市衛(wèi)生局科研基金2006-2009,第一承擔(dān)人(2010年結(jié)題)
(5) "乳腺癌患者來源抗體庫的構(gòu)建",天津市教委重點基金項目(07JCYBJC09100) 2006-2009,第三承擔(dān)人(2010年結(jié)題)
(6) "SLP-2基因在常見惡性腫瘤中的表達(dá)及與預(yù)后關(guān)系研究",天津醫(yī)科大學(xué)科研基金,2005-2007,第五承擔(dān)人,已結(jié)題并成果登記(2008年)
(7) "不同來源TIMP-1表達(dá)對腫瘤細(xì)胞生物特性影響的研究",天津市衛(wèi)生局科研基金,2005-2008,第二承擔(dān)人,已結(jié)題,已結(jié)題并成果登記(2008年)
發(fā)表文章
(1) Xu-Chen Cao, Wei-Ran Zhang, Wen-Feng Cao, Bo-Wen Liu, Fei Zhang, Hong-Meng Zhao, Ran Meng, Lin Zhang, Rui-Fang Niu, Xi-Shan Hao, Bin Zhang. Aquaporin 3 is required for FGF-2-induced migration of human breast cancers. (PLOS ONE,Accepted)
(2) Xu-Chen Cao, Wei-Ran Zhang, Wen-Feng Cao, Bo-Wen Liu, Fei Zhang, Hong-Meng Zhao, Ran Meng, Lin Zhang, Rui-Fang Niu, Xi-Shan Hao, Bin Zhang. PKCδ regulates AQP3-dependent cell migration of human breast cancers via PI3K/AKT/mTOR signaling. (Breast cancer research and treatment, under review)
(3) Han YW, Yu ZH, Wen SY, Zhang Bin, Cao XC and Wang X. Prognostic value of hemotherapy-induced neutropenia in early-stage breast cancer. Breast Cancer Res Treat. 2012 Jan;131(2):483-90. (SCI收錄,IF:4.859)
(4) F. Zhang, X. Zhang, M. Li, P. Chen, B. Zhang, H. Guo, W. Cao, X. Wei, X. Cao, X. Hao and N. Zhang .mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis. Cancer Res. 2011;70(22):9360-70.
(5) Wang X, Zhao Y, Cao X*. Clinical benefits of mastectomy on treatment of occult breast carcinoma presenting axillary metastases. Breast J. 2010;16:32-7.
(6) Zhang B, Cao W, Zhang F, Zhang L, Niu R, Niu Y, Fu L, Hao X, Cao X*. Protein interacting with C alpha kinase 5 (PICK1) is involved in promoting tumor growth and correlates with poor prognosis of human breast cancer. Cancer Sci. 2010 Mar
(7) Chang XZ, Yu J, Zhang XH, Yin J, Wang T, Cao XC*. Enhanced expression of trophinin promotes invasive and metastatic potential of human gallbladder cancer cells. J Cancer Res ClinOncol. 2009;135:581-90.
(8) Zhang B, Cao X, Liu Y, Cao W, Zhang F, Zhang S, Li H, Ning L, Fu L, Niu Y, Niu R, Sun B, Hao X. Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer. BMC Cancer. 2008;8:83.
(9) Cao W, Zhang B, Liu Y, Li H, Zhang S, Fu L, Niu Y, Ning L, Cao X, Liu Z, Sun B. High-level SLP-2 expression and HER-2/neu protein expression are associated with decreased breast cancer patient survival. Am J ClinPathol. 2007;128:430-6.
(10) Li X, Cao X, Li X, Zhang W, Feng Y. Expression level of insulin-like growth factor binding protein 5 mRNA is a prognostic factor for breast cancer. CancerSci. 2007 ;98:1592-6.
(11) Niu Y, Fu XL, Yu Y, Wang PP, Cao XC*. Intra-operative frozen section diagnosis of breast lesions: a retrospective analysis of 13,243 Chinese patients. Chin Med J (Engl). 2007;120:630-5.
(12)馮煒紅,張斌,曹旭晨*.上皮-間質(zhì)轉(zhuǎn)化與乳腺癌.國際腫瘤學(xué)雜志,2011,38: 121-123
(13)李媛媛,張斌,曹旭晨*.組蛋白脫乙?;敢种苿┰谀[瘤治療中的應(yīng)用.國際腫瘤學(xué)雜志. 2011,38:424-426.
(14)劉博文,張斌,曹旭晨*.樹突狀細(xì)胞免疫治療的新進(jìn)展.國際腫瘤學(xué)雜志. 2011, 38: 20-23.
(15)陳祖錦,張斌綜述,曹旭晨*審校.自噬與腫瘤治療.國際腫瘤學(xué)雜志.2011,38:170-172.
(16)劉博文,張斌,張偉然,張月,馮緯紅,李媛媛,曹旭晨*. 3-甲基腺苷對芹菜素誘導(dǎo)乳腺癌T47D細(xì)胞系自噬和凋亡的影響.中國腫瘤臨床. 2011, 38:1318-1321
(17)劉博文,張斌,張月,馮緯紅,李媛媛,張偉然,曹旭晨*.芹菜素誘導(dǎo)乳腺癌T47D細(xì)胞株自噬的研究.中華實驗外科雜志. 2011,28:2000-2000.
(18)韓蕓蔚,王欣,張斌,溫紹艷,劉偉,曹旭晨*。新輔助化療誘導(dǎo)的粒細(xì)胞減少癥對乳腺癌預(yù)后的影響.中華普通外科雜志2011;8:651-654.
(19)宋艷群,張斌,曹旭晨*,趙洪猛,等.陽性淋巴結(jié)比率對腋窩淋巴結(jié)受累乳腺癌患者總生存率的影響.實用腫瘤雜志,2011, 26:33-36.
(20)宋艷群,張斌,曹旭晨,趙洪猛,等. Akt抑制劑MK2206對乳腺癌細(xì)胞增殖和凋亡的影響.腫瘤,2011, 31(2):131-135.
(21)張斌,曹文楓,高宇,潘思虎,劉巖雪,寧連勝,郝希山,曹旭晨*.陽性-檢查淋巴結(jié)比例(PER)在腋淋巴結(jié)陽性乳腺癌的預(yù)后意義.中華普通外科雜志.2010; 25: 418-419
(22)張斌,馮銳,潘思虎,曹文楓,劉巖雪,喬群,曹旭晨*.大鼠腹壁動脈穿支皮瓣模型的建立.中華實驗外科雜志.2010;27:125-127
(23)趙洪猛,張斌,姚慧,李小莉,宋艷群,王鑫,劉曉霞,曹旭晨*. FGFR2基因多態(tài)性與乳腺癌易感性的相關(guān)研究.中國腫瘤臨床. 2010;37:626-629
(24)宋艷群,張斌,趙洪猛,曹旭晨*.乳腺癌結(jié)外浸潤對不同水平腋窩淋巴結(jié)受累患者預(yù)后的影響.中國腫瘤臨床.2010;37:862-865
(25)任莉,張斌,曹旭晨,陳瑛,葛潔.熒光定量PCR分析FGFR2基因多態(tài)性與乳腺癌的相關(guān)性研究.中華醫(yī)學(xué)遺傳學(xué)雜志2010;27:445-448.
(26)張斌,孟然,趙洪猛,曹旭晨*.隱匿性乳腺癌的臨床診治要點.中國腫瘤臨床. 2010; 37: 477-480
(27)陳祖錦,張斌,曹旭晨*.Bcl-2蛋白小分子抑制劑的研究進(jìn)展.國際腫瘤學(xué)雜志. 2010; 37: 579-581
(28)劉博文,張斌,陳祖錦,曹旭晨*.芹菜素抗腫瘤機制研究進(jìn)展.國際腫瘤學(xué)雜志. 2010, 37:824-827.
(29)張月,張斌,馮瑋紅,曹旭晨*等.Aurora激酶抑制劑對乳腺癌細(xì)胞增殖和凋亡的影響.中華實驗外科雜志.2012,29:74-76.
(30)張月,張斌,馮瑋紅,曹旭晨*等.PHA739358抑制乳腺癌細(xì)胞增殖、誘導(dǎo)凋亡的分子機制.中華醫(yī)學(xué)雜志.2012,92:45-49.
出診時間:每周四上午乳腺腫瘤門診